Hopantenic acid
Names | |
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Preferred IUPAC name 4-[(2R)-2,4-Dihydroxy-3,3-dimethylbutanamido]butanoic acid | |
Identifiers | |
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3D model (JSmol) | |
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ChemSpider | |
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PubChem CID | |
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CompTox Dashboard (EPA) | |
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Properties | |
C10H19NO5 | |
Molar mass | 233.264 g·mol−1 |
Related compounds | |
Related alkanoic acids | |
Related compounds | Panthenol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Hopantenic acid (homopantothenic acid), also known as N-pantoyl-GABA, is a central nervous system depressant. Formulated as the calcium salt, it is used as a pharmaceutical drug in the Russian Federation for a variety of neurological, psychological and psychiatric conditions and sold as Pantogam (Russian: Пантогам).[1]
Chemistry
[edit]Hopantenic acid is a homologue of pantothenic acid. While pantothenic acid is the amide of D-pantoate and β-alanine, hopantenic acid is the amide of D-pantoate and γ-aminobutyric acid (GABA). This change leads to an additional CH2 in the molecule.[2]
See also
[edit]References
[edit]- ^ "Hopantenic acid". DrugBank. Retrieved 2023-09-18.
- ^ Kopelevich VM, Evdokimova GS, Marieva TD, Shmuilovich LM (1971). "Synthesis of D-homopantothenic acid". Pharmaceutical Chemistry Journal. 5 (9): 534–536. doi:10.1007/BF00771659. S2CID 33296093.
External links
[edit]- pantogab (hopantenic acid) - Curehunter.com