3-Quinuclidinyl thiochromane-4-carboxylate
Chemical compound
Identifiers | |
---|---|
| |
CAS Number | |
PubChem CID | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C17H21NO2S |
Molar mass | 303.42 g·mol−1 |
3D model (JSmol) | |
| |
|
3-Quinuclidinyl thiochromane-4-carboxylate is a research compound which is one of the most potent muscarinic antagonists known. Tests in vitro showed it to have a binding affinity over 1000 times more potent than 3-quinuclidinyl benzilate.[1][2]
See also
[edit]References
[edit]- ^ Cohen VI, Gibson RE, Reba RC (October 1987). "Synthesis and structure-activity relationships of new muscarinic antagonists". Journal of Pharmaceutical Sciences. 76 (10): 848–50. doi:10.1002/jps.2600761020. PMID 3430351.
- ^ Ball JC (2015). "Dual Use Research of Concern: Derivatives of 3-Quinuclidinyl Benzilate". Military Medical Science Letters. 84 (1): 2–41. doi:10.31482/mmsl.2015.001.
mAChRsTooltip Muscarinic acetylcholine receptors |
| ||||
---|---|---|---|---|---|
Precursors (and prodrugs) | |||||
This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
Retrieved from "https://en.wikipedia.org/w/index.php?title=3-Quinuclidinyl_thiochromane-4-carboxylate&oldid=1241820745"