Gestation is the period of development during the carrying of an embryo, and later fetus, inside viviparous animals (the embryo develops within the parent). It is typical for mammals, but also occurs for some non-mammals. Mammals during pregnancy can have one or more gestations at the same time, for example in a multiple birth.
The time interval of a gestation is called the gestation period. In obstetrics, gestational age refers to the time since the onset of the last menses, which on average is fertilization age plus two weeks.
In humans, pregnancy can be defined clinically or biochemically. Clinically, pregnancy starts from the mother's last missed period. Biochemically, pregnancy starts when a woman's human Chorionic Gonadotropin (hCG) levels rise above 25 mIU/mL.
Human pregnancy can be divided into three trimesters, each approximately three months long: the first, second, and third trimester. The first trimester is from the last menstrual period through the 13th week, the second trimester is 14th–28/29th week, and the third trimester is 29/30th–42nd week. Birth normally occurs at a gestational age of about 40 weeks, though it is common for births to occur from 37 to 42 weeks. Labor occurring prior to 37 weeks gestation is considered preterm labor and can result from multiple factors, including previous preterm deliveries.
Prenatal care is important for the maintenance of a healthy pregnancy and surveillance of related complications. In high-income countries, prenatal care typically involves monthly visits during the first two trimesters, with an increasing number of visits closer to delivery. At these visits, healthcare providers will evaluate a variety of parental and fetal metrics, including fetal growth and heart rate, birth defects, maternal blood pressure, among others.
After birth, health care providers will measure the baby's weight, vital signs, reflexes, head circumference, muscle tone, and posture to help determine the gestational age.
Various factors can influence the duration of gestation, including diseases in pregnancy and adequate prenatal care. The rates of morbidity and pre-existing diseases that predispose mothers to life-threatening, pregnancy-related complications in the United States are increasing. The brunt of this burden is experienced by non-Hispanic Black women. Inaccessibility of prenatal care may partially explain this ongoing disparity. Other factors that affect prenatal care utilization include socioeconomic status, insurance status, childcare, social support, housing, and immigration status.
In viviparous animals, the embryo develops inside the body of the mother, as opposed to outside in an egg (oviparity). The mother then gives live birth. The less developed form of viviparity is called ovoviviparity, in which the mother carries embryos inside eggs. Most vipers exhibit ovoviviparity. The more developed form of viviparity is called placental viviparity; mammals are the best example, but it has also evolved independently in other animals, such as in scorpions, some sharks, and in velvet worms. Viviparous offspring live independently and require an external food supply from birth. Certain lizards also employ this method such as the genera Tiliqua and Corucia. The placenta is attached directly to the mother in these lizards which is called viviparous matrotrophy.
Ovoviviparous animals develop within eggs that remain within the mother's body up until they hatch or are about to hatch. It is similar to viviparity in that the embryo develops within the mother's body. Unlike the embryos of viviparous species, ovoviviparous embryos are nourished by the egg yolk rather than by the mother's body. However, the mother's body does provide gas exchange. The young of ovoviviparous amphibians are sometimes born as larvae, and undergo metamorphosis outside the body of the mother.
The fish family Syngnathidae has the unique characteristic whereby females lay their eggs in a brood pouch on the male's chest, and the male incubates the eggs. Fertilization may take place in the pouch or before implantation in the water. Included in Syngnathidae are seahorses, the pipefish, and the weedy and leafy sea dragons. Syngnathidae is the only family in the animal kingdom to which the term "male pregnancy" has been applied.
- Evolution of mammals (for the evolution of gestation-related features in humans and other mammals)
- Male pregnancy
- Nesting instinct
- Pregnancy in fish
- Prenatal development
- Prenatal nutrition and birth weight
- Mckay RJ, Lucey JF (June 1964). "NEONATOLOGY". The New England Journal of Medicine. 270 (23): 1231–6 CONTD. doi:10.1056/NEJM196406042702306. PMID 14132827.
- Keith L, Oleszczuk JJ (January 1999). "Iatrogenic multiple birth, multiple pregnancy and assisted reproductive technologies". International Journal of Gynaecology and Obstetrics. 64 (1): 11–25. doi:10.1016/S0020-7292(98)00230-6. PMID 10190665. S2CID 31814692.
- Liao JB, Buhimschi CS, Norwitz ER (June 2005). "Normal labor: mechanism and duration". Obstetrics and Gynecology Clinics of North America. 32 (2): 145–64, vii. doi:10.1016/j.ogc.2005.01.001. PMID 15899352.
- "What is HCG?". American Pregnancy Association. 2020-04-26. Retrieved 2021-09-13.
- "How Your Baby Grows During Pregnancy" (PDF). American College of Obstetricians and Gynecologists.
- Griggs KM, Hrelic DA, Williams N, McEwen-Campbell M, Cypher R (November 2020). "Preterm Labor and Birth: A Clinical Review". MCN: The American Journal of Maternal/Child Nursing. 45 (6): 328–337. doi:10.1097/NMC.0000000000000656. PMID 33074911. S2CID 224813648.
- "Preterm Labor and Birth". www.acog.org. Retrieved 2021-09-13.
- Helton MR (March 1997). "Prenatal care". Primary Care. 24 (1): 135–46. PMID 9016732.
- "Gestational age: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 2021-09-13.
- Coley SL, Aronson RE (September 2013). "Exploring Birth Outcome Disparities and the Impact of Prenatal Care Utilization Among North Carolina Teen Mothers". Women's Health Issues. 23 (5): e287–e294. doi:10.1016/j.whi.2013.06.004.
- "Exploring the social determinants of racial/ethnic disparities in prenatal care utilization and maternal outcome". Seminars in Perinatology. 41 (5): 308–317. 2017-08-01. doi:10.1053/j.semperi.2017.04.008. ISSN 0146-0005.
- Gadson A, Akpovi E, Mehta PK (August 2017). "Exploring the social determinants of racial/ethnic disparities in prenatal care utilization and maternal outcome". Seminars in Perinatology. 41 (5): 308–317. doi:10.1053/j.semperi.2017.04.008. PMID 28625554.
- Neill WT (1964-01-01). "Viviparity in Snakes: Some Ecological and Zoogeographical Considerations". The American Naturalist. 98 (898): 35–55. doi:10.1086/282299. ISSN 0003-0147. S2CID 85209921.
- Bainbridge DR (November 2014). "The evolution of pregnancy". Early Human Development. 90 (11): 741–5. doi:10.1016/j.earlhumdev.2014.08.013. PMID 25242206.
- Carter AM, Soma H (August 2020). "Viviparity in the longest-living vertebrate, the Greenland shark (Somniosus microcephalus)". Placenta. 97: 26–28. doi:10.1016/j.placenta.2020.05.014. PMID 32792058. S2CID 221121663.
- Smith MR (October 2016). "Evolution: Velvet Worm Biogeography". Current Biology. 26 (19): R882–R884. doi:10.1016/j.cub.2016.07.067. PMID 27728789. S2CID 4039461.
- Munns SL, Edwards A, Nicol S, Frappell PB (March 2015). "Pregnancy limits lung function during exercise and depresses metabolic rate in the skink Tiliqua nigrolutea". The Journal of Experimental Biology. 218 (Pt 6): 931–9. doi:10.1242/jeb.111450. PMID 25788728. S2CID 16426853.
- Hutchin K (2021-07-19). "Prehensile-tailed Skink". Ambassador Animal. Retrieved 2021-09-19.
- Ostrovsky AN, Lidgard S, Gordon DP, Schwaha T, Genikhovich G, Ereskovsky AV (August 2016). "Matrotrophy and placentation in invertebrates: a new paradigm". Biological Reviews of the Cambridge Philosophical Society. 91 (3): 673–711. doi:10.1111/brv.12189. PMC 5098176. PMID 25925633.
- Mueller LD, Bitner K (December 2015). "The Evolution of Ovoviviparity in a Temporally Varying Environment". The American Naturalist. 186 (6): 708–15. doi:10.1086/683661. PMID 26655978. S2CID 7447706.
- Thompson MB (December 2007). "Comparison of the respiratory transition at birth or hatching in viviparous and oviparous amniote vertebrates". Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology. 148 (4): 755–60. doi:10.1016/j.cbpa.2007.01.006. PMID 17314056.
- Cook DF, Voss SC, Dadour IR (November 2012). "The laying of live larvae by the blowfly Calliphora varifrons (Diptera: Calliphoridae)". Forensic Science International. 223 (1–3): 44–6. doi:10.1016/j.forsciint.2012.07.015. PMID 22921421.
- Scobell SK, Mackenzie DS (June 2011). "Reproductive endocrinology of Syngnathidae". Journal of Fish Biology. 78 (6): 1662–80. doi:10.1111/j.1095-8649.2011.02994.x. PMID 21651522.
- Wilson AB, Orr JW (June 2011). "The evolutionary origins of Syngnathidae: pipefishes and seahorses". Journal of Fish Biology. 78 (6): 1603–23. doi:10.1111/j.1095-8649.2011.02988.x. PMID 21651519.
- Jones AG, Avise JC (October 2003). "Male pregnancy". Current Biology. 13 (20): R791. doi:10.1016/j.cub.2003.09.045. PMID 14561416.