French
DeutschAntiglucocorticoid
Class of pharmaceutical drugs
 | This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. Find sources: "Antiglucocorticoid" – news · newspapers · books · scholar · JSTOR (February 2024) (Learn how and when to remove this message) |
| Antiglucocorticoid | |
|---|---|
| Drug class | |
 Mifepristone, an antiglucocorticoid that is used in the treatment of Cushing's syndrome. | |
| Class identifiers | |
| Synonyms | Glucocorticoid antagonist; Cortisol antagonist; Anticorticosteroid |
| Use | Cushing's syndrome, others |
| Biological target | Glucocorticoid receptor |
| Chemical class | Steroids |
| Legal status | |
| In Wikidata | |
An antiglucocorticoid is a drug which reduces glucocorticoid activity in the body.[1] They include direct glucocorticoid receptor antagonists such as mifepristone and synthesis inhibitors such as metyrapone, ketoconazole, and aminoglutethimide. They are used to treat Cushing's syndrome.
Antiglucocorticoids could be effective antidepressants for a subset of specific mood disorders, but their use is limited by side effects.
See also
[edit]References
[edit]- ^ Muller, Caroline; Hennebert, Olivier; Morfin, Robert (2006-07-01). "The native anti-glucocorticoid paradigm". The Journal of Steroid Biochemistry and Molecular Biology. 100 (1): 95–105. doi:10.1016/j.jsbmb.2006.03.001. ISSN 0960-0760.
| Glucocorticoids | |
|---|---|
| Antiglucocorticoids |
|
| Synthesis modifiers | |
| |
 | This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |