U.S. Route 278 (US 278) is a 146.130-mile (235.173 km) east–west United States highway that traverses through the South Carolina Lowcountry, from North...

U.S. Route 278 (US 278) is a parallel route of US 78. It currently runs for 1,074 miles (1,728 km) from Hilton Head Island, South Carolina, to Wickes,...

Nine special routes of U.S. Route 278 currently exist. Four of them lie within the state of Arkansas. One more existed in the past but has since been decommissioned...

U.S. Route 78 (US 78) is a 142.207-mile (228.860 km) U.S. highway that travels from Cash, Arkansas to Charleston, South Carolina. In the U.S. state of...

U.S. Route 278 (US 278) in the U.S. state of Georgia is an east–west United States Highway traversing the north-central portion of the state. The highway...

U.S. Highway 1 (US 1) is a 170.540-mile (274.458 km) north–south U.S. Highway that crosses South Carolina from southwest to northeast and connects the...

U.S. Highway 17 (US 17) is a 221.454-mile (356.396 km) north–south United States Numbered Highway in the U.S. state of South Carolina located near the...

U.S. Route 76 (US 76) is an east–west U.S. highway in the U.S. state of South Carolina. Being one of the longest and most important highways in the state...

U.S. Route 601 (US 601) is a north–south United States highway that runs for 316.3 miles (509.0 km) from U.S. Route 321, near Tarboro, South Carolina...

U.S. Route 321 (US 321) is a spur of U.S. Route 21. It runs for 516.9 miles (831.9 km) from Hardeeville, South Carolina to Lenoir City, Tennessee; with...