 | Phosphoinositide 3-kinase inhibitors (PI3K inhibitors) are a class of medical drugs that are mainly used to treat advanced cancers. They function by inhibiting... 44 KB (5,305 words) - 21:36, 24 March 2024 |
 | Phosphoinositide 3-kinases (PI3Ks), also called phosphatidylinositol 3-kinases, are a family of enzymes involved in cellular functions such as cell growth... 32 KB (3,463 words) - 17:34, 20 November 2023 |
 | Wortmannin (category Phosphoinositide 3-kinase inhibitors) inhibitor of phosphoinositide 3-kinases (PI3Ks). It has an in vitro inhibitory concentration (IC50) of around 5 nM, making it a more potent inhibitor... 12 KB (1,138 words) - 05:28, 7 May 2024 |
Phosphoinositide 3-kinase#Class I Phosphoinositide 3-kinase inhibitor Stein RC (September 2001). "Prospects for phosphoinositide 3-kinase inhibition as a cancer... 3 KB (281 words) - 17:41, 25 April 2024 |
 | Leniolisib (category Phosphoinositide 3-kinase inhibitors) selective phosphoinositide 3-kinase inhibitor (PI3Kδ inhibitor), which means it blocks a form of the protein called phosphoinositide 3-kinase delta (PI3Kδ)... 9 KB (583 words) - 17:26, 7 February 2024 |
 | Idelalisib (category Phosphoinositide 3-kinase inhibitors) acts as a phosphoinositide 3-kinase inhibitor; more specifically, it blocks P110δ, the delta isoform of the enzyme phosphoinositide 3-kinase. It was developed... 15 KB (1,245 words) - 06:10, 10 April 2024 |
 | the field of biochemistry, PDPK1 refers to the protein 3-phosphoinositide-dependent protein kinase-1, an enzyme which is encoded by the PDPK1 gene in humans... 18 KB (2,127 words) - 19:11, 8 April 2024 |
for the activity of the enzyme, and 3-phosphoinositide-dependent protein kinase-1 (PDPK1) is the upstream kinase responsible for initiating the process... 27 KB (2,650 words) - 21:16, 19 March 2024 |
 | the di-phosphorylated phosphoinositide PIP2 is only phosphorylated by the family of enzymes, PI 3-kinases (phosphoinositide 3-kinase or PI3-K), and only... 34 KB (3,754 words) - 20:14, 23 April 2024 |
 | Eganelisib (category Phosphoinositide 3-kinase inhibitors) treatment for cancer. It is a highly selective phosphoinositide 3-kinase inhibitor, and thus works by inhibiting the enzyme PIK3CG, disrupting the PI3K/AKT/mTOR... 7 KB (479 words) - 08:15, 7 February 2024 |