In organic chemistry, the Paal–Knorr synthesis is a reaction used to synthesize substituted furans, pyrroles, or thiophenes from 1,4-diketones. It is a...

group α to (bonded to the next carbon to) a carbonyl group (2). In the Paal–Knorr pyrrole synthesis, a 1,4-dicarbonyl compound reacts with ammonia or a...

pyrrole. There are a number of important syntheses of pyrroles that are operated in the manner of the Knorr Synthesis, despite having mechanisms of very...

side-chain. Several laboratory syntheses of roseophilin (e.g., those of Trost, Fürstner, Salamone) are based upon the Paal-Knorr synthesis, and two others...

the reaction of 1,4-diketones with phosphorus pentoxide (P2O5) in the Paal–Knorr synthesis. Many routes exist for the synthesis of substituted furans....

Oxidation of alcohols to carbonyl compounds Ozonolysis Paal–Knorr pyrrole synthesis Paal–Knorr synthesis Paneth technique Passerini reaction Paternò–Büchi...

features an oxidative coupling of two benzylic carbons, as well as a Paal-Knorr pyrrole synthesis. The Banwell group’s synthesis of lamellarin K includes...

dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Specialized thiophenes can be synthesized similarly...

acetonylacetone. 1,4-Diketones are useful precursors to heterocycles via the Paal–Knorr synthesis, which gives pyrroles: This reactivity is the basis of the neurotoxicity...