• Thumbnail for PIEZO2
    mechanosensitive ion channel component 2 is a protein that in humans is encoded by the PIEZO2 gene. It has a homotrimeric structure, with three blades curving into a...
    10 KB (1,030 words) - 02:06, 3 December 2023
  • Thumbnail for Ardem Patapoutian
    Armenian descent. He is known for his work in characterizing the PIEZO1, PIEZO2, and TRPM8 receptors that detect pressure, menthol, and temperature. Patapoutian...
    32 KB (2,464 words) - 19:14, 8 March 2024
  • Thumbnail for PIEZO1
    close homolog PIEZO2 were cloned in 2010, using an siRNA-based screen for mechanosensitive ion channels. PIEZO1 (this gene) and PIEZO2 share 47% identity...
    13 KB (1,345 words) - 00:15, 24 February 2024
  • Thumbnail for Merkel cell
    system. Merkel cells express PIEZO2, a mechanosensitive ion channel that responds to mechanical forces. Mice in which Piezo2 is knocked-out specifically...
    9 KB (996 words) - 03:15, 11 March 2024
  • Thumbnail for Proprioception
    in the PIEZO2 gene exhibit specific deficits in joint proprioception, as well as vibration and touch discrimination, suggesting that the PIEZO2 channel...
    56 KB (6,842 words) - 03:26, 15 March 2024
  • excitatory signals via ion conductance on mechanosensitive channels. of which Piezo2 is the Merkel cell's primary mechanosensor. The Merkel cell's somewhat rigid...
    7 KB (1,029 words) - 15:59, 23 October 2023
  • Thumbnail for Baroreflex
    mechanosensitivity is hypothesised to be linked to the expression of PIEZO1 and PIEZO2 on neurons in the petrosal and nodose ganglia. Baroreceptor action potentials...
    13 KB (1,562 words) - 02:34, 2 January 2024
  • Thumbnail for Chilean rose tarantula
    News. Jan 1, 2010. Retrieved 3 January 2010. "Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage"...
    12 KB (1,407 words) - 18:11, 5 January 2024
  • Thumbnail for University of California, San Francisco
    Nobel Prize laureate known for his work in characterizing the PIEZO1, PIEZO2, and TRPM8 receptors William W. Parmley – Former Editor of the Journal of...
    89 KB (9,572 words) - 19:07, 24 March 2024
  • Thumbnail for 2021 in science
    for [i.a.] temperature and touch [the discovery/mechanics of TRPV1 and PIEZO2] Nobel Prize in Physics – Syukuro Manabe and Klaus Hasselmann (1/2) "for...
    296 KB (38,834 words) - 08:05, 8 March 2024