• Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics. Commonly...
    22 KB (2,572 words) - 18:37, 23 February 2024
  • Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure (sequence). The technique...
    79 KB (9,462 words) - 18:31, 28 January 2024
  • open reading frames. Although oligonucleotide probes are often used in "spotted" microarrays, the term "oligonucleotide array" most often refers to a...
    54 KB (5,427 words) - 14:19, 26 April 2024
  • An allele-specific oligonucleotide (ASO) is a short piece of synthetic DNA complementary to the sequence of a variable target DNA. It acts as a probe...
    10 KB (1,292 words) - 20:49, 18 September 2023
  • Thumbnail for Fluorescein amidite
    fluorescein dye used in oligonucleotide synthesis and molecular biology. FAM is used in the preparation of fluorescein-labeled oligonucleotide probes for the detection...
    1 KB (87 words) - 15:24, 16 February 2023
  • Antisense therapy is a form of treatment that uses antisense oligonucleotides (ASOs) to target messenger RNA (mRNA). ASOs are capable of altering mRNA...
    23 KB (2,212 words) - 22:18, 9 November 2023
  • Thumbnail for CpG oligodeoxynucleotide
    Zimmermann S, Albrecht I, Heeg K (May 2002). "Phosphodiester CpG oligonucleotides as adjuvants: polyguanosine runs enhance cellular uptake and improve...
    11 KB (1,393 words) - 18:39, 23 February 2024
  • Thumbnail for Systematic evolution of ligands by exponential enrichment
    combinatorial chemistry technique in molecular biology for producing oligonucleotides of either single-stranded DNA or RNA that specifically bind to a target...
    41 KB (4,741 words) - 05:07, 22 April 2024
  • Thumbnail for Antibody-oligonucleotide conjugate
    Antibody-oligonucleotide conjugates or AOCs belong to a class of chimeric molecules combining in their structure two important families of biomolecules:...
    19 KB (1,967 words) - 15:04, 11 December 2023
  • link each molecule of a chemically synthesized entity to a particular oligonucleotide sequence constructed in parallel and to use this encoding genetic tag...
    42 KB (4,740 words) - 18:06, 26 April 2024