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    ORF3a (previously known as X1 or U274) is a gene found in coronaviruses of the subgenus Sarbecovirus, including SARS-CoV and SARS-CoV-2. It encodes an...
    10 KB (998 words) - 09:48, 17 February 2024
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    and Orf3a-mediated HMGB1 release and cell death in lung cells expressing SARS-CoV-2 viral proteins. Glycyrrhizin did not only reverse S-RBD- and Orf3a-induced...
    31 KB (3,699 words) - 07:27, 22 March 2024
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    nucleocapsid (N). The later ORFs also encode for eight unique proteins (orf3a to orf9b), known as the accessory proteins, many with no known homologues...
    52 KB (5,878 words) - 23:00, 7 May 2024
  • SARS-CoV-2 virus. Specifically, AlphaFold 2's prediction of the structure of the ORF3a protein was very similar to the structure determined by researchers at University...
    62 KB (6,610 words) - 04:35, 11 May 2024
  • accessory proteins of SARS-CoV-2, especially several overlapping genes with ORF3a. The predicted protein product of the ORF3c gene has at least once been...
    6 KB (538 words) - 23:28, 2 December 2023
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    comparison tools. It also features a frame-shift deletion of four nucleotides in ORF3a that generates a stop codon two amino acids. The mutation is labeled as...
    27 KB (2,258 words) - 22:09, 2 November 2023
  • Thumbnail for P24 capsid protein
    VSPs: viral envelope Spike Envelope Membrane Nucleocapsid VNPs: ORF1ab 3C-like protease (NS5) ORF3a ORF3b ORF3c ORF3d ORF6 ORF7a ORF7b ORF8 ORF9b...
    13 KB (1,460 words) - 08:22, 9 May 2024
  • nucleocapsid protein (N); and five viral accessory proteins, including ORF3a (NS3), ORF6 (NS6), ORF7a (NS7a), ORF7b (NS7b) and ORF8 (NS8). RaTG13 bears...
    12 KB (1,792 words) - 13:05, 12 December 2023
  • accessory proteins of SARS-CoV-2, especially several overlapping genes with ORF3a. Due to differences in the genomes of SARS-CoV and SARS-CoV-2, two distinct...
    10 KB (1,093 words) - 00:30, 3 December 2023
  • other SARSr-CoV (by nucleotide %) Strain Full-length genome ORF1ab S RBM ORF3a E M ORF6 ORF7a ORF7b ORF8 N ORF10 RaTG13 96.10% 96.50% 92.30% 86.30% 96...
    6 KB (762 words) - 03:50, 12 December 2023