Isogenic human disease models are a family of cells that are selected or engineered to accurately model the genetics of a specific patient population...

Isogenic may refer to: Zygosity Isogenic human disease models Isogenous (disambiguation) This disambiguation page lists articles associated with the title...

creating viral vectors for gene therapy, and for the creation of isogenic human disease models. Gene therapy vectors using AAV can infect both dividing and...

adopted for use in engineering human cell lines to generate isogenic human disease models. It has also been used to optimize bioproducer cell lines for...

nucleases, have enabled the creation of a new generation of isogenic human disease models. The term episome was introduced by François Jacob and Élie...

also used to create a new generation of genetic disease models called isogenic human disease models. ZFNs can be used to disable dominant mutations in...

accurate, isogenic human disease models. These engineered human cell models are thought to more accurately reflect the genetics of human diseases than their...

engineer rat cell models, advances in gene targeting technologies enable a new wave of isogenic human disease models. These models are the most accurate...

taken to model long QT syndrome in cardiomyocytes derived from pluripotent stem cells. These CRISPR-generated cellular models, with isogenic controls...

an isogenic control, which can be performed simultaneously with iPSC reprogramming. Comparison of a patient iPSC derived organoid against an isogenic control...