An iminosugar, also known as an iminosaccharide, is any analog of a sugar where a nitrogen atom has replaced the oxygen atom in the ring of the structure...

N-acetylation will furnish the desired 2-N-acetamido-2-deoxyglycosides. Iminosugar N-Acetylglucosamine Galactosamine Glucosamine Sialic acid L-Daunosamine...

due to various mutations, one of which is called N370S. Afegostat, an iminosugar, binds selectively to N370S glucocerebrosidase and restores its correct...

mainly obtained from a class of Streptomyces species. Chemically, it is an iminosugar. 1-deoxynojirimycin or duvoglustat 1-deoxygalactonojirimycin or migalastat...

strains of streptomycetes, e.g. Streptomyces azureus. Nojirimycin, an iminosugar from a class of Streptomyces species. Tetrodotoxin, a neurotoxin produced...

Castanospermine is an indolizidine alkaloid first isolated from the seeds of Castanospermum australe. It is a potent inhibitor of some glucosidase enzymes...

Swainsonine is an indolizidine alkaloid. It is a potent inhibitor of Golgi alpha-mannosidase II, an immunomodulator, and a potential chemotherapy drug...

doesn't work; this is called substrate reduction therapy. Miglustat is an iminosugar, a synthetic analogue of D-glucose and a white to off-white crystalline...

collectively as pyrrolizidine alkaloids. It is one of five classes of iminosugars. These are often synthesized from a carbohydrate. Pyrrolizidine alkaloids...

northern Brazil in northern South America. Members of this genus accumulate iminosugars in their leaves. Ten species are accepted: Alexa bauhiniiflora Ducke...