• Thumbnail for EPAS1
    domain-containing protein 1 (EPAS1, also known as hypoxia-inducible factor-2alpha (HIF-2α)) is a protein that is encoded by the EPAS1 gene in mammals. It is...
    22 KB (2,679 words) - 23:01, 23 March 2024
  • Thumbnail for Tibetan Mastiff
    deeply-diverged from modern Holarctic wolves and dogs has contributed the EPAS1 allele found in both Himalayan wolves and dogs, and this allows them to...
    20 KB (2,395 words) - 07:24, 18 April 2024
  • Per-Arnt-Sim (PAS) domain protein 1 (EPAS1). It was found that one single-nucleotide polymorphism (SNP) at EPAS1 shows a 78% frequency difference between...
    53 KB (5,800 words) - 23:48, 22 April 2024
  • Thumbnail for Organisms at high altitude
    continents. Tibetan humans and Tibetan domestic dogs share a genetic mutation in EPAS1, but it has not been seen in Andean humans. Tardigrades live over the entire...
    52 KB (5,491 words) - 09:14, 3 December 2023
  • Thumbnail for Tibetan people
    that make Tibetans' bodies well-suited for high-altitudes, including the EPAS1 gene, also referred to as the "super-athlete gene", which regulates the...
    47 KB (4,697 words) - 01:42, 27 April 2024
  • Thumbnail for Denisovan
    brown eyes. The Denisovan genome also contains a variant region around the EPAS1 gene that in Tibetans assists with adaptation to low oxygen levels at high...
    68 KB (7,083 words) - 22:25, 29 April 2024
  • Thumbnail for Sherpa people
    factors that make Tibetans' bodies well-suited for high altitudes, including EPAS1, referred to as the "super-athlete gene," that regulates the body's production...
    45 KB (5,017 words) - 01:26, 27 April 2024
  • Thumbnail for Human evolution
    Tibetans evolving over 3,000 years to have high proportions of an allele of EPAS1 that is adaptive to high altitudes. Other evolution is related to endemic...
    253 KB (26,316 words) - 14:01, 29 April 2024
  • Thumbnail for Zinc finger
    n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
    42 KB (4,825 words) - 15:48, 31 January 2024
  • ENSG00000163508 T-box Known motif – High-throughput in vitro [202] WTCACACCTH EPAS1 ENSG00000116016 bHLH Known motif – In vivo/Misc source [203] VDACGTGHH ERF...
    374 KB (81 words) - 02:10, 23 September 2023