response. The potency of an agonist is inversely related to its EC50 value. The EC50 can be measured for a given agonist by determining the concentration... 14 KB (1,618 words) - 23:34, 19 April 2024 |
Threshold dose (section EC50) toxicology, there are some other safety factors including LD50, LC50 and EC50. Threshold dose is a dose of drug barely adequate to produce a biological... 23 KB (2,910 words) - 06:26, 27 September 2023 |
the 5-HT2A receptor, with an EC50 of 185.7 nM and an efficacy of 28.7% (vs 5-HT), and a full agonist at 5-HT2C with an EC50 of 89.7 nM and an efficacy of... 2 KB (121 words) - 00:40, 14 February 2024 |
on binding affinity. Potency of drug is the measure of its effectiveness, EC50 is the drug concentration of a drug that produces an efficacy of 50% and... 48 KB (4,743 words) - 16:19, 27 April 2024 |
inhibition at CB1 it displays a similar efficacy to that of Δ9-THC (EC50 = 11 nM vs. EC50 = 5.2 nM, respectively), but a lower maximum response (Emax = 28%... 7 KB (650 words) - 16:31, 28 April 2024 |