Transcription factor E2F4 is a protein that in humans is encoded by the E2F4 gene. The protein encoded by this gene is a member of the E2F family of transcription...
9 KB (1,287 words) - 16:22, 22 December 2023
are activators: E2F1, 2 and E2F3a. Six others act as suppressors: E2F3b, E2F4-8. All of them are involved in the cell cycle regulation and synthesis of...
16 KB (1,910 words) - 11:56, 3 May 2024
acetyltransferases, which activate gene expression necessary for G1 entry, while E2F4 complexes recruit histone deacetylases, which repress gene expression. Phosphorylation...
30 KB (3,755 words) - 01:51, 4 April 2024
64648 IRMNG: 1286850 ITIS: 94169 NBN: NBNSYS0000175931 NCBI: 371448 NZOR: f7633344-e2f4-4774-b5b9-808e541ffd1f Open Tree of Life: 1011199 WoRMS: 101571...
3 KB (225 words) - 16:55, 9 February 2024
ENSG00000112242 E2F Known motif – High-throughput in vitro [173] TTTTGGCGCCMTTTTY E2F4 ENSG00000205250 E2F Known motif – High-throughput in vitro [174] TTTGGCGCCAAA...
374 KB (81 words) - 02:10, 23 September 2023
are homologs of RB (p105) and bind repressive E2F transcription factors E2F4 and E2F5; DP1, DP2 and DP3, dimerization partners of E2F; and MuvB, which...
25 KB (3,065 words) - 20:39, 30 October 2023
Homo sapiens basic transcription factor 3 E2F4 Homo sapiens E2F transcription factor 4, p107/p130-binding (E2F4), mRNA ERH (gene) Enhancer of rudimentary...
48 KB (4,612 words) - 23:41, 12 December 2023
Cdk1/FOXO1/Bad pathway (Giovanni et al., 2000). The downregulation of p130/E2F4 (a complex which has been shown to maintain the post mitotic nature of neurons)...
13 KB (2,128 words) - 18:24, 27 April 2024
present, a repressor complex composed of Smad3, and the transcription factors E2F4 and p107 exist in the cytoplasm. However, when TGF-B signal is present, this...
35 KB (4,581 words) - 08:50, 23 March 2024
E2F1, E2F2 and E2F3 while the repressor E2Fs are E2F4, E2F5 and E2F6. Activator E2Fs along with E2F4 bind exclusively to pRb. pRb is able to bind to the...
79 KB (9,499 words) - 02:45, 29 March 2024