Derek Christopher Shepherd, M.D., F.A.C.S., also referred to as "McDreamy", is a fictional surgeon from the ABC medical drama Grey's Anatomy, portrayed...

series Private Practice in the recurring role of Amelia Shepherd, the sister of Derek Shepherd from its parent show, Grey's Anatomy. Eric Stoltz, who was...

maintaining the relationship with her one-night stand and eventual husband, Derek Shepherd (McDreamy), her motherhood, and her friendships with her colleagues...

California. Addison joined the series in the first-season finale as Derek Shepherd (Patrick Dempsey)'s estranged wife. Initially set for a recurring guest...

they divorced in the third season. Derek is the father of Zola Grey Shepherd, Derek Bailey Shepherd, and Ellis Shepherd. In season 11, episode 21, "How To...

(Chandra Wilson), a senior resident, who works with attending physicians Derek Shepherd (Patrick Dempsey), head of neurosurgery and who also happens to be Meredith's...

introduced in season two as Derek Shepherd's best friend. Mark caused the end of Derek’s marriage by sleeping with Derek's then-wife, Addison Montgomery...

continue her role as Dr. Amelia Shepherd, one of Dr. Derek Shepherd's four sisters. Scorsone previously played Dr. Amelia Shepherd in the seventh season as a...

initially focusing on neurosurgery during her residency due to her crush on Derek Shepherd, April Kepner finally settles on trauma surgery as a specialty. After...

surgery. Meredith is in a romantic relationship with her attending Derek Shepherd (Patrick Dempsey) a stranger she had a one-night stand with, and is...