A de novo mutation (DNM) is any mutation or alteration in the genome of an individual organism (human, animal, plant, microbe, etc.) that was not inherited...

beginning', 'anew'. De novo may also refer to: De novo mutation, a new germline mutation not inherited from either parent De novo protein design, the...

only have occurred from at least one de novo germline mutation in the history of human evolution. De novo mutations have also been researched as playing...

September 2018. Chandley AC (April 1991). "On the parental origin of de novo mutation in man". Journal of Medical Genetics. 28 (4): 217–23. doi:10.1136/jmg...

in a gene or chromosome. The mutation responsible can occur spontaneously before embryonic development (a de novo mutation), or it can be inherited from...

of a mutation spectrum is the distribution of rates for all individual mutations that might happen in a genome (e.g., ). From this full de novo spectrum...

caused by a mutation in the ASXL3 gene, which is considered a de novo mutation. Genetic changes that are described as de novo (new) mutations can be either...

cases of CSS appear to be the result of a de novo mutation. This syndrome has been associated with mutations in the ARID1B gene, which is the most prevalent...

be the result of spontaneous mutation in an ancestor. Victoria's appears to have been a spontaneous or de novo mutation, most likely inherited from one...

behaviors in girls, and in boys the mutation is embryonic lethal. Besides these early examples, the role of de novo mutations in autism first became evident...