• Thumbnail for CpG site
    along its 5' → 3' direction. CpG sites occur with high frequency in genomic regions called CpG islands. Cytosines in CpG dinucleotides can be methylated...
    51 KB (5,474 words) - 16:32, 19 April 2024
  • Thumbnail for Epigenetics
    methylated CpG site (a cytosine followed by guanine along its 5' → 3' direction and where the cytosine is methylated (5-mCpG)). A 5-mCpG site has the lowest...
    161 KB (18,430 words) - 15:53, 26 April 2024
  • CpG may refer to: CpG site - methylated sequences of DNA significant in gene regulation CpG island - regions of DNA that contain several CpG sites CpG...
    280 bytes (65 words) - 09:35, 25 January 2024
  • Thumbnail for DNA methylation
    occurs on the cytosine nucleotide in a CpG site, in plants the cytosine can be methylated at CpG, CpHpG, and CpHpH sites, where H represents any nucleotide...
    115 KB (13,262 words) - 14:22, 26 April 2024
  • Thumbnail for 8-Oxo-2'-deoxyguanosine
    (CpG sites). In the mouse brain, 4.2% of all cytosines are methylated, primarily in the context of CpG sites, forming 5mCpG. Most hypermethylated 5mCpG...
    25 KB (2,763 words) - 21:16, 13 April 2024
  • Thumbnail for DNA demethylation
    CpG site). In mammals, DNA methyltransferases (which add methyl groups to DNA bases) exhibit a strong sequence preference for cytosines at CpG sites....
    42 KB (5,154 words) - 13:37, 14 February 2024
  • Thumbnail for Regulation of gene expression
    differentially methylated CpG sites returned to the level of never-smokers within five years of smoking cessation. However, 2,568 CpGs among 942 genes remained...
    45 KB (5,229 words) - 20:42, 1 May 2024
  • Thumbnail for DNA repair
    methylated CpG site (a cytosine followed by guanine along its 5' → 3' direction and where the cytosine is methylated (5-mCpG)). A 5-mCpG site has the lowest...
    128 KB (15,713 words) - 22:17, 26 April 2024
  • Thumbnail for TET enzymes
    along its 5' → 3' direction (at CpG sites). This forms a 5mCpG site. More than 98% of DNA methylation occurs at CpG sites in mammalian somatic cells. Thus...
    32 KB (3,984 words) - 05:42, 27 April 2024
  • Thumbnail for Reactive oxygen species
    a demethylation pathway shown in the second figure. The thousands of CpG sites being demethylated during memory formation depend on ROS in an initial...
    73 KB (8,480 words) - 17:09, 1 April 2024