• Thumbnail for Coelenterazine
    Coelenterazine is a luciferin, a molecule that emits light after reaction with oxygen, found in many aquatic organisms across eight phyla. It is the substrate...
    9 KB (741 words) - 16:04, 3 December 2023
  • Thumbnail for Aequorin
    prosthetic group coelenterazine, the luciferin. This is to say, apoaequorin is the enzyme produced in the photocytes of the animal, and coelenterazine is the substrate...
    29 KB (3,171 words) - 19:54, 6 April 2024
  • chemiluminescence. Unlike luminol, coelenterazine does not require any catalyst to trigger luminescence. Analogs of coelenterazine such as CLA (2-methyl-6-phenyl-3...
    15 KB (1,741 words) - 05:55, 29 April 2024
  • Thumbnail for Luciferin
    mononucleotide and a fatty aldehyde found in bioluminescent bacteria. Coelenterazine is found in radiolarians, ctenophores, cnidarians, squid, brittle stars...
    9 KB (867 words) - 20:20, 25 April 2024
  • Thumbnail for Bioluminescence
    triphosphate (ATP). In evolution, luciferins vary little: one in particular, coelenterazine, is found in 11 different animal phyla, though in some of these, the...
    74 KB (8,010 words) - 00:07, 3 May 2024
  • Thumbnail for Renilla-luciferin 2-monooxygenase
    bioluminescent enzyme found in Renilla reniformis, belonging to a group of coelenterazine luciferases. Of this group of enzymes, the luciferase from Renilla reniformis...
    11 KB (1,251 words) - 15:41, 26 August 2023
  • Thumbnail for Luciferase
    fluorescent protein (GFP). Calcium triggers release of the luciferin (coelenterazine) from the luciferin binding protein. The substrate is then available...
    27 KB (2,896 words) - 13:08, 29 March 2024
  • Thumbnail for Förster resonance energy transfer
    patented substrate for NanoLuc called furimazine, though other valuables coelenterazine substrates for NanoLuc have also been published. A split-protein version...
    52 KB (6,145 words) - 10:08, 6 January 2024
  • apoaequorin, the luminophore coelenterazine, and molecular oxygen. These proteins function together. As calcium binds to coelenterazine, (a bioluminescent molecule...
    2 KB (248 words) - 22:17, 29 December 2023
  • Thumbnail for Roger Y. Tsien
    its prosthetic group coelenterazine is consumed irreversibly when emits light, thus requires continuous addition of coelenterazine into the media. To overcome...
    41 KB (3,938 words) - 18:34, 6 April 2024