 | Cellular senescence is a phenomenon characterized by the cessation of cell division. In their experiments during the early 1960s, Leonard Hayflick and... 57 KB (6,395 words) - 02:55, 28 March 2024 |
proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication In a decadal... 57 KB (7,511 words) - 13:29, 12 April 2024 |
 | P16 (section Role in cellular senescence) protects against cancer while increasing the risks associated with cellular senescence. p16 is an inhibitor of cyclin-dependent kinases (CDK). It slows... 36 KB (4,236 words) - 01:25, 8 April 2024 |
 | Hayflick limit (redirect from Replicative senescence) would have been subject to the 50 ± 10 mitosis event limit until cellular senescence occurs as described in Hayflick's findings. Hayflick first became... 16 KB (1,876 words) - 19:40, 20 April 2024 |
Programmed cell death (redirect from Cell senescence and death) Programmed cell death (PCD; sometimes referred to as cellular suicide) is the death of a cell as a result of events inside of a cell, such as apoptosis... 53 KB (6,348 words) - 09:40, 28 April 2024 |
three major types of cellular senescence, namely replicative senescence, oncogene-induced senescence and DNA damage-induced senescence are descriptions of... 73 KB (7,941 words) - 07:55, 30 April 2024 |
instability can lead to cellular senescence, and thus to SASP The high-mobility group proteins (HMGA) can induce senescence and SASP in a p53-dependent... 36 KB (4,073 words) - 22:51, 9 April 2024 |
 | Lipopolysaccharide (section Cellular senescence) important and harmful role in autoimmunity, obesity, depression, and cellular senescence. The toxic activity of LPS was first discovered and termed endotoxin... 59 KB (6,752 words) - 14:50, 21 March 2024 |
 | CD36 (section Establishment of cellular senescence) establishment of cellular senescence". EMBO Reports. 19 (6). doi:10.15252/embr.201745274. PMC 5989758. PMID 29777051. Moiseeva V, et al. (2022). "Senescence atlas... 45 KB (5,199 words) - 23:44, 3 January 2024 |
Hallmarks of aging (category Senescence) to damage) Deregulated nutrient sensing Mitochondrial dysfunction Cellular senescence Integrative hallmarks (culprits of the phenotype) Stem cell exhaustion... 40 KB (4,312 words) - 19:06, 19 April 2024 |