Cluster of differentiation 40, CD40 is a type I transmembrane protein found on antigen-presenting cells and is required for their activation. The binding...

CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules...

to continue the immune response can come from B7-CD28 and CD40–CD40L interactions. When CD40 on the APC binds CD40L(CD154) on the T cell, signals are sent...

antigen on MHC class II proteins, a CD4+ cell will aid those cells through a combination of cell to cell interactions (e.g. CD40 (protein) and CD40L) and through...

crucial in the IL-17 signaling pathway. Moreover, this protein is only used in cells expressing CD40 and CD40L, which are also from the tumor necrosis receptor...

Heat shock proteins (HSPs) are a family of proteins produced by cells in response to exposure to stressful conditions. They were first described in relation...

(November 2009). "A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific...

which codes for CD40 ligand. This gene is located on the long arm of the X chromosome at position 26, denoted Xq26. Normally, CD40 ligand is expressed...

as tumor necrosis factor ligand superfamily member 13 (TNFSF13), is a protein of the TNF superfamily recognized by the cell surface receptor TACI. It...

mediated by CD40 signalling. Once the naïve CD8+ T cell is bound to the infected cell, the infected cell is triggered to release CD40. This CD40 release,...