• Thumbnail for CD19
    B-lymphocyte antigen CD19, also known as CD19 molecule (Cluster of Differentiation 19), B-Lymphocyte Surface Antigen B4, T-Cell Surface Antigen Leu-12...
    32 KB (3,948 words) - 16:55, 26 January 2024
  • dual targeting of CD19 plus CD22 or CD19 plus CD20 have demonstrated promise, and trials studying bispecific targeting to circumvent CD19 down-regulation...
    76 KB (8,019 words) - 16:39, 29 April 2024
  • Anti-CD19 immunotoxin is a monoclonal antibody linked to a toxic substance. It is being studied in the treatment of some types of B-cell cancer. Anti-CD19...
    576 bytes (87 words) - 04:47, 24 February 2017
  • immunity. Solid tumours don't express CD19 on their cell surface, therefore introducing the CF33-CD19 allowed for CD19 to be present on the solid tumour cell...
    6 KB (831 words) - 04:20, 1 December 2023
  • and neurological toxicities. Due to CD19 being a pan-B cell marker, the T-cells that are engineered to target CD19 receptors on the cancerous B cells also...
    17 KB (1,241 words) - 00:45, 19 April 2024
  • system to act against tumor cells. Blinatumomab specifically targets the CD19 antigen present on B cells. In December 2014, it was approved by the US Food...
    12 KB (995 words) - 05:47, 10 April 2024
  • humanised monoclonal antibody that binds CD19 and Fc gamma receptor IIb to inhibit B cells, plasmablasts, and CD19-expressing plasma cells." Perugino, Cory...
    4 KB (217 words) - 05:06, 31 January 2024
  • Thumbnail for Complement receptor 2
    Complement receptor 2 interacts with CD19, and, on mature B cells, forms a complex with CD81 (TAPA-1). The CR2-CD19-CD81 complex is often called the B cell...
    14 KB (1,830 words) - 18:43, 3 May 2024
  • Thumbnail for Plasma cell
    surface antigens, and do not express common pan-B cell markers, such as CD19 and CD20. Instead, plasma cells are identified through flow cytometry by...
    24 KB (2,785 words) - 12:01, 19 April 2024
  • Thumbnail for Diffuse large B-cell lymphoma
    B-cells based on their expression of B-cell marker proteins (e.g. CD20, CD19, CD22, CD79, PAX5, BOB1, OCT2, an immunoglobulin [usually IgM but occasionally...
    69 KB (8,143 words) - 18:36, 22 January 2024