involve the creation of artificial APCs to prime the adaptive immune system to target malignant cells. Antigen-presenting cells fall into two categories:...

Artificial antigen presenting cells (aAPCs) are engineered platforms for T-cell activation. aAPCs are used as a new technology and approach to cancer...

microenvironment. Mesenchymal stem cell derived nanoghosts exhibit cancer targeting properties. Artificial Antigen Presenting Cells (aAPCs) are polystyrene beads...

biology, chimeric antigen receptors (CARs)—also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors—are receptor...

number of other particles can qualify as artificial cells. The terms "artificial cell" and "synthetic cell" are used in a variety of different fields...

specific cell types and cytokines to persist. Plasma cells will secrete huge quantities of antibody regardless of whether or not their cognate antigen is present...

dendritic cell.[citation needed] With the exception of non-nucleated cells (including erythrocytes), all cells are capable of presenting antigen through...

upon T cell activation, and TGF-β from any of a variety of sources, including tolerizing dendritic cells (DCs), other antigen presenting cells, or in...

by antigen-presenting cells. Co-stimulation of the B cell by activated T cell resulting in its complete activation. Proliferation of B cells with resultant...

normal cells but are activated in cancer cells or peptides containing cancer-specific mutations. Antigen-presenting cells (APCs) such as dendritic cells take...