Apoptosis signal-regulating kinase 1 (ASK1) also known as mitogen-activated protein kinase 5 (MAP3K5) is a member of MAP kinase family and as such a part...
19 KB (2,219 words) - 06:02, 11 March 2024
cellular communication in plants. Thioredoxin has been shown to interact with: ASK1, Collagen, type I, alpha 1, Glucocorticoid receptor, SENP1, TXNIP. NF-κB...
25 KB (2,845 words) - 00:21, 10 March 2024
targeting upstream MAPKs, such as ASK1. Studies in animal models of inflammatory arthritis have yielded promising results, and ASK1 has recently been found to...
46 KB (5,501 words) - 14:24, 23 February 2024
although it acts on ASK1, which is upstream of JNK. The mechanism and result are similar to that of GSTP and JNK, in that GSTM1 sequesters ASK1 through complex...
38 KB (4,278 words) - 10:20, 13 December 2023
MEKK1) MAP3K2 (aka MEKK2) MAP3K3 (aka MEKK3) MAP3K4 (aka MEKK4) MAP3K5 (aka ASK1) MAP3K6 (aka ASK2) MAP3K7 (aka MEKK7) (aka TAK1) MAP3K8 (aka TPL2 or Tpl2)...
11 KB (1,345 words) - 09:11, 2 January 2024
species. The interaction between ASK1 and STRAP is characterized by specific domains, with the C-terminal domain of ASK1 and the fourth and sixth WD40 repeats...
18 KB (2,082 words) - 04:07, 27 April 2024
UV-radiation. ASK1 will be transported to the nucleus when UV-irradiation is used to treat the cell. It is still unknown as to whether ASK1 binds Daxx,...
11 KB (1,528 words) - 20:53, 21 December 2023
activates the JNK-inducing upstream kinases of MLK2/MLK3, TAK1, MEKK1 and ASK1 (either directly or through GCKs and Trx, respectively). SRC- Vav- Rac axis...
52 KB (6,302 words) - 07:19, 27 April 2024
inflammation and cell adhesion in rheumatoid arthritis synovial fibroblasts by ASK1 regulation". Toxicology and Applied Pharmacology. 287 (3): 299–305. doi:10...
63 KB (6,881 words) - 20:37, 14 May 2024
product is functionally redundant. PDCD6 has been shown to interact with ASK1, PDCD6IP, Fas receptor, ANXA11 and PEF1. GRCh38: Ensembl release 89: ENSG00000249915...
10 KB (1,245 words) - 17:12, 12 May 2024