Opioids are a class of drugs that derive from, or mimic, natural substances found in the opium poppy plant. Opioids work in the brain to produce a variety...
221 KB (19,665 words) - 02:56, 12 May 2024
The opioid epidemic, also referred to as the opioid crisis, is the rapid increase in the overuse, misuse/abuse, and overdose deaths attributed either...
70 KB (7,300 words) - 19:00, 16 April 2024
Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins...
40 KB (4,427 words) - 12:37, 12 January 2024
Opioid use disorder (OUD) is a substance use disorder characterized by cravings for opioids, continued use despite physical and/or psychological deterioration...
119 KB (12,649 words) - 16:38, 15 April 2024
An opioid antagonist, or opioid receptor antagonist, is a receptor antagonist that acts on one or more of the opioid receptors. Naloxone and naltrexone...
11 KB (1,340 words) - 23:11, 28 April 2024
The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins...
22 KB (2,424 words) - 08:47, 18 May 2024
An opioid overdose is toxicity due to excessive consumption of opioids, such as morphine, codeine, heroin, fentanyl, tramadol, and methadone. This preventable...
48 KB (4,919 words) - 15:23, 15 April 2024
There is an ongoing opioid epidemic (also known as the opioid crisis) in the United States, originating out of both medical prescriptions and illegal...
251 KB (26,023 words) - 15:30, 15 May 2024
The κ-opioid receptor or kappa opioid receptor, abbreviated KOR or KOP for its ligand ketazocine, is a G protein-coupled receptor that in humans is encoded...
67 KB (7,675 words) - 03:40, 2 May 2024
Benzimidazole opioids, also known as nitazenes, are a class of synthetic opioids with an unusual benzimidazole structure often referred to as "opioid New Psychoactive...
24 KB (1,556 words) - 16:41, 21 May 2024