The κ-opioid receptor or kappa opioid receptor, abbreviated KOR or KOP for its ligand ketazocine, is a G protein-coupled receptor that in humans is encoded...
67 KB (7,675 words) - 03:40, 2 May 2024
agonist action at the κ-opioid receptor. As they induce opioid withdrawal effects in people who are taking, or have recently used, opioid full agonists, these...
11 KB (1,340 words) - 03:04, 25 May 2024
Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins...
40 KB (4,427 words) - 12:37, 12 January 2024
The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins...
22 KB (2,424 words) - 08:47, 18 May 2024
Opioid peptides or opiate peptides are peptides that bind to opioid receptors in the brain; opiates and opioids mimic the effect of these peptides. Such...
19 KB (1,419 words) - 18:28, 15 March 2024
Agonist-antagonist (redirect from Agonist–antagonist opioid)
at κ-opioid receptor and antagonist activity at the delta opioid receptor (δ) nalbuphine, κ-agonist/μ-antagonist analgesic Agonist–antagonist opioids usually...
7 KB (715 words) - 18:05, 18 February 2024
The δ-opioid receptor, also known as delta opioid receptor or simply delta receptor, abbreviated DOR or DOP, is an inhibitory 7-transmembrane G-protein...
28 KB (3,359 words) - 21:06, 7 June 2024
Buprenorphine/samidorphan (ALKS-5461) – κ-opioid receptor antagonist and μ-opioid receptor antagonist CVL-354 – selective κ-opioid receptor antagonist BTRX-246040 (LY-2940094)...
28 KB (2,260 words) - 20:35, 4 June 2024
ISSN 0040-4020. Santino, Federica; Gentilucci, Luca (January 2023). "Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with...
13 KB (1,218 words) - 05:12, 3 April 2024
Carfentanil (category Mu-opioid receptor agonists)
values (Ki) of 0.051 nM for the μ-opioid receptor, 4.7 nM for the δ-opioid receptor, and 13 nM for the κ-opioid receptor in rat brain. Thus, carfentanil...
22 KB (2,039 words) - 01:20, 2 May 2024