• Thumbnail for Nonsense-mediated decay
    Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that exists in all eukaryotes. Its main function is to reduce errors in gene expression by...
    16 KB (2,066 words) - 06:36, 27 December 2023
  • Thumbnail for Messenger RNA
    subject to surveillance by nonsense-mediated decay (NMD), which checks for the presence of premature stop codons (nonsense codons) in the message. These...
    49 KB (5,922 words) - 00:21, 9 May 2024
  • nonsense-mediated mRNA decay pathway (NMD); the nonstop mediated mRNA decay pathways (NSD); and the no-go mediated mRNA decay pathway (NGD). Nonsense-mediated...
    29 KB (3,394 words) - 21:28, 16 March 2024
  • Thumbnail for Exon junction complex
    splicing, but along with Y14, it also takes part in the process of nonsense-mediated decay in eukaryotes. SRm160 is another coactivator that has been proposed...
    21 KB (2,530 words) - 20:28, 20 May 2024
  • Thumbnail for Eukaryotic translation termination factor 1
    recognition in translation, termination of translation, and nonsense mediated mRNA decay via the SURF complex. All cells need to make proteins through...
    43 KB (5,516 words) - 15:21, 19 May 2024
  • Thumbnail for Nuclear cap-binding protein complex
    ways that it does this quality control is through nonsense-mediated decay. Nonsense-mediated decay is when faulty mRNA's that have stop codons too early...
    12 KB (1,489 words) - 04:47, 22 December 2023
  • Thumbnail for UPF1
    between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa...
    11 KB (1,401 words) - 22:24, 16 March 2024
  • Thumbnail for SR protein
    alternative pre-mRNA splicing, mRNA export, genome stabilization, nonsense-mediated decay, and translation. SR proteins alternatively splice pre-mRNA by...
    27 KB (3,445 words) - 02:41, 3 December 2023
  • lower species, such as yeast—employ a nonsense-mediated mRNA decay pathway, which degrades mRNAs containing nonsense mutations before they are able to be...
    25 KB (2,870 words) - 22:43, 9 March 2024
  • Thumbnail for Non-stop decay
    In contrast to nonsense-mediated decay (NMD), polypeptides do not release from the ribosome, and thus, NSD seems to involve mRNA decay factors distinct...
    7 KB (1,014 words) - 04:04, 10 June 2023