AMBRA1 (activating molecule in Beclin1-regulated autophagy) is a protein that is able to regulate cancer cells through autophagy. AMBRA1 is described as...
15 KB (1,622 words) - 14:37, 10 January 2024
AMACR HGNC:451 Q9UHK6 611 AMBN HGNC:452 Q9NP70 612 AMBP HGNC:453 P02760 613 AMBRA1 HGNC:25990 Q9C0C7 614 AMD1 HGNC:457 P17707 615 AMDHD1 HGNC:28577 Q96NU7...
277 KB (17 words) - 23:17, 27 April 2024
Piacentini M, Cecconi F, Fimia GM (October 2010). "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy". The Journal...
75 KB (8,905 words) - 05:54, 13 May 2024
genes encoding proteins containing this domain include: AAAS, AAMP, AHI1, AMBRA1, APAF1, ARPC1A, ARPC1B, ATG16L1, BOP1, BRWD1, BRWD3, BTRC, BUB3, C6orf11...
13 KB (956 words) - 05:47, 30 January 2023
ananassa Duch., cv. Nyoho) were investigated for phytohormonal treatments. Ambra1 is a positive regulator of autophagy, a lysosome-mediated degradative process...
69 KB (6,804 words) - 04:42, 27 April 2024
phosphorylation of threonine 286 and subsequent ubiquitylation via the CRL4-AMBRA1 E3 ubiquitin ligase complex. Cyclin D1 overexpression has been shown to...
49 KB (5,694 words) - 22:42, 27 March 2024
Y, Liao G, Tu H, Huang Y, Peng T, et al. (February 2022). "The role of ambra1 in Pb-induced developmental neurotoxicity in zebrafish". Biochemical and...
3 KB (360 words) - 11:15, 18 October 2023
transiently degraded by the proteasome upon its ubiquitylation by the CRL4-AMBRA1 ubiquitin ligase. This degradation causes release of p21 from Cdk4 complexes...
39 KB (4,605 words) - 22:37, 27 March 2024