CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47...
36 KB (4,214 words) - 05:29, 27 May 2024
inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don't eat me" signal. This interaction negatively controls...
13 KB (1,664 words) - 15:41, 23 December 2023
Cancer immunotherapy (section Anti-CD47 therapy)
effectiveness. Many tumor cells overexpress CD47 to escape immunosurveilance of host immune system. CD47 binds to its receptor signal-regulatory protein...
90 KB (9,943 words) - 09:46, 14 May 2024
marker CD47 was found to have anti-phagocytic signals to macrophages and inhibits natural killer (NK) cells. This enabled researchers to apply CD47 as a...
13 KB (1,342 words) - 23:15, 28 May 2024
NI-1701, an anti-CD47, anti-CD19 bispecific antibody in development for treatment of B-cell hematological cancers. NI-1801, an anti-CD47, anti-mesothelin...
4 KB (361 words) - 03:09, 9 March 2023
CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55 CD56 CD57 CD58...
11 KB (1,311 words) - 20:50, 18 October 2022
Election Returns: District Definitions California Voter Foundation map - CD47 33°46′59″N 117°53′57″W / 33.783024°N 117.899206°W / 33.783024; -117.899206...
41 KB (907 words) - 02:27, 21 February 2024
February 10, 1999 Socorro LINEAR · 4.0 km MPC · JPL 31479 Botello 1999 CD47 Botello February 10, 1999 Socorro LINEAR V 3.1 km MPC · JPL 31480 Jonahbutler...
192 KB (274 words) - 17:38, 30 November 2023
is the presence of another molecule with signal CD47, which blocks CRT. Hence antibodies that block CD47 might be useful as a cancer treatment. In mice...
20 KB (2,452 words) - 02:06, 10 March 2024
other "eat-me" signals, such as calreticulin. "Don't-eat-me" signals include CD47, which when expressed on the surface of a cell, inhibit phagocytosis of that...
9 KB (1,318 words) - 13:37, 9 May 2024