Tuberous sclerosis complex (TSC) is a rare multisystem autosomal dominant genetic disease that causes non-cancerous tumours to grow in the brain and on...
50 KB (5,493 words) - 07:36, 3 June 2024
The history of tuberous sclerosis (TSC) research spans less than 200 years. TSC is a rare, multi-system genetic disease that can cause benign tumours to...
51 KB (5,417 words) - 21:47, 29 November 2023
the skin, and in some cases also blood vessels and internal organs. Tuberous sclerosis, a rare genetic disease which affects multiple systems. "Welcome To...
3 KB (290 words) - 21:13, 31 December 2023
TSC1 (redirect from Tuberous sclerosis 1)
Tuberous sclerosis 1 (TSC1), also known as hamartin, is a protein that in humans is encoded by the TSC1 gene. TSC1 functions as a co-chaperone which inhibits...
20 KB (2,424 words) - 14:23, 6 May 2024
TSC2 (redirect from Tuberous sclerosis 2)
Tuberous sclerosis complex 2 (TSC2), also known as tuberin, is a protein that in humans is encoded by the TSC2 gene. Mutations in this gene lead to tuberous...
16 KB (1,843 words) - 05:18, 15 April 2024
Tuberous sclerosis proteins 1 and 2, also known as TSC1 (hamartin) and TSC2 (tuberin), form a protein-complex. The encoding two genes are TSC1 and TSC2...
9 KB (1,075 words) - 08:43, 5 January 2024
Benign tumor (section Tuberous sclerosis complex)
apoptosis (programmed cell death), causing the growth of benign tumors. Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder caused by...
32 KB (3,494 words) - 09:30, 12 May 2024
Angiomyolipomas are strongly associated with the genetic disease tuberous sclerosis, in which most individuals have several angiomyolipomas affecting...
17 KB (1,950 words) - 18:54, 1 December 2023
Sirolimus (section Tuberous sclerosis complex)
indicated for the treatment of facial angiofibroma associated with tuberous sclerosis complex. The chief advantage sirolimus has over calcineurin inhibitors...
68 KB (6,765 words) - 17:51, 7 June 2024
commonly develop in individuals who have the rare genetic disease, tuberous sclerosis (a heritable neurocutaneous disorder) and uncommonly in individuals...
12 KB (1,379 words) - 21:01, 6 January 2024