Lonafarnib, sold under the brand name Zokinvy, is a medication used to reduce the risk of death due to Hutchinson-Gilford progeria syndrome and for the...
15 KB (1,042 words) - 05:37, 3 February 2024
syndrome In November 2020, the U.S. Food and Drug Administration approved lonafarnib, which helps prevent buildup of defective progerin and similar proteins...
59 KB (6,094 words) - 15:22, 31 May 2024
Progerin (section Lonafarnib)
causing the rapid aging effects you see in HGPS. Researchers are exploring lonafarnib (a farnesyltransferase inhibitor) as a potential pharmacological therapy...
9 KB (1,036 words) - 15:42, 31 May 2024
coated". dailymed.nlm.nih.gov. Retrieved 2021-07-01. "DailyMed - ZOKINVY- lonafarnib capsule". dailymed.nlm.nih.gov. Retrieved 2021-07-01. "DailyMed - DUPIXENT-...
11 KB (842 words) - 13:15, 12 February 2024
activation of anti-viral cell mediated immunity. The prenylation inhibitor lonafarnib prevents hepatitis D viral particle assembly by inhibiting the farnesylation...
50 KB (5,940 words) - 02:50, 28 February 2024
others have entered clinical trials for different cancers. SCH66336 (Lonafarnib) was the first to do so, followed by R115777 (Zarnestra, Tipifarnib)....
12 KB (1,079 words) - 17:42, 26 May 2021
of progeria, and in May 2007 a phase II clinical trial using the FTI lonafarnib was started for children with progeria. In signal transduction via G protein...
15 KB (1,810 words) - 11:18, 31 March 2024
lomifylline (INN) lomitapide (USAN, INN) Lomotil (Pfizer) lomustine (INN) lonafarnib (USAN) lonapalene (INN) lonaprisan (USAN) lonaprofen (INN) lonazolac (INN)...
6 KB (345 words) - 06:55, 1 June 2024
In 2020 the American Food and Drug Administration approved the use of lonafarnib in children with the disease based on research and funding provided by...
3 KB (287 words) - 08:18, 4 January 2024
A16AX17 Triheptanoin A16AX18 Lumasiran A16AX19 Fosdenopterin A16AX20 Lonafarnib A16AX21 Elivaldogene autotemcel A16AX22 Tiomolibdic acid A16AX23 Leriglitazone...
3 KB (358 words) - 02:46, 18 December 2023