Half maximal effective concentration (EC50) is a measure of the concentration of a drug, antibody or toxicant which induces a biological response halfway...
9 KB (1,024 words) - 06:20, 19 February 2024
IC50 is comparable to other measures of potency, such as EC50 for excitatory drugs. EC50 represents the dose or plasma concentration required for obtaining...
10 KB (1,072 words) - 06:17, 20 May 2024
response. The potency of an agonist is inversely related to its EC50 value. The EC50 can be measured for a given agonist by determining the concentration...
14 KB (1,618 words) - 23:34, 19 April 2024
compared to D9-THC (1.6x). 9R-HHC has an EC50 of 3.4nM ± 1.5nM at CB1 and 6.2nM ± 2.1nM at CB2 while 9S-HHC has an EC50 of 57nM ± 19nM at CB1 and 55nM ± 10nM...
18 KB (1,834 words) - 04:27, 12 June 2024
as EC50, IC50, ED50, etc.) and measures of efficacy (such as tissue, cell or population response). A commonly used dose–response curve is the EC50 curve...
17 KB (1,788 words) - 12:43, 12 December 2023
the 5-HT2A receptor, with an EC50 of 185.7 nM and an efficacy of 28.7% (vs 5-HT), and a full agonist at 5-HT2C with an EC50 of 89.7 nM and an efficacy of...
2 KB (121 words) - 00:40, 14 February 2024
Threshold dose (section EC50)
toxicology, there are some other safety factors including LD50, LC50 and EC50. Threshold dose is a dose of drug barely adequate to produce a biological...
23 KB (2,910 words) - 06:26, 27 September 2023
as a strong non-competitive selective NMDA receptor antagonist, with an EC50 of 20 μM; which might promote sedation in addition with the strong antihistaminergic...
32 KB (2,681 words) - 11:10, 25 May 2024
EK45 Westover March 9, 2000 Socorro LINEAR · 4.0 km MPC · JPL 17237 2000 EC50 — March 7, 2000 Višnjan Observatory K. Korlević · 2.9 km MPC · JPL 17238...
194 KB (274 words) - 01:54, 30 April 2024
eliciting 50% of its maximal effect (half maximal effective concentration = EC50) at the human 5-HT2A receptor in vitro are in the 0.118–0.983 μmol/L range...
144 KB (14,308 words) - 23:20, 16 June 2024