In electrophilic aromatic substitution reactions, existing substituent groups on the aromatic ring influence the overall reaction rate or have a directing...

Electrophilic aromatic substitution (SEAr) is an organic reaction in which an atom that is attached to an aromatic system (usually hydrogen) is replaced...

protecting groups can be used to prevent electrophilic aromatic substitution. They can also be installed as directing groups to affect the position where a substitution...

yellow flame, due to high C:H ratio Undergo electrophilic substitution reactions and nucleophilic aromatic substitutions Arenes are typically split into...

groups deactivate (slow) the reaction and directs the electrophilic nitronium ion to attack the aromatic meta position. Deactivating meta-directing substituents...

Electrophilic fluorination is the combination of a carbon-centered nucleophile with an electrophilic source of fluorine to afford organofluorine compounds...

assistance from the meta-directing group influencing the positioning of the incoming substituent. For example, the electrophilic aromatic nitration of 1-methyl-3-nitrobenzene...

takes the form of 3 main steps shown below; Forming of a π-complex The electrophilic Br-Br molecule interacts with electron-rich alkene molecule to form...

electrophilic aromatic substitution. Trimethylsilyl, tert-butyl, and isopropyl groups can form stable carbocations, hence are ipso directing groups....

Directed ortho metalation (DoM) is an adaptation of electrophilic aromatic substitution in which electrophiles attach themselves exclusively to the ortho-...