Friedreich's ataxia (FRDA or FA) is an autosomal-recessive genetic disease that causes difficulty walking, a loss of coordination in the arms and legs...
48 KB (5,038 words) - 08:49, 5 March 2024
different possible causes. Ataxia can be limited to one side of the body, which is referred to as hemiataxia. Friedreich's ataxia has gait abnormality as...
55 KB (5,946 words) - 10:57, 23 May 2024
Idebenone (section Friedreich's ataxia (Sovrima))
neuromuscular diseases. In 2010, early clinical trials for the treatment of Friedreich's ataxia and Duchenne muscular dystrophy have been completed. As of December 2013[update]...
15 KB (1,513 words) - 22:47, 26 February 2024
apraxia (AOA), spastic ataxia. Disorder subdivisions: Friedreich's ataxia, spinocerebellar ataxia, ataxia telangiectasia, vasomotor ataxia, vestibulocerebellar...
37 KB (2,946 words) - 13:44, 18 May 2024
are fragile X syndrome, several spinocerebellar ataxias, myotonic dystrophy and Friedreich's ataxia. The first documentation of anticipation in genetic...
61 KB (7,973 words) - 04:54, 27 May 2024
Repeated sequence (DNA) (section Friedreich's Ataxia)
have been linked to human diseases such as Huntington's disease and Friedreich's ataxia. Some repetitive elements are neutral and occur when there is an...
31 KB (3,686 words) - 18:49, 6 May 2024
The Friedreich's Ataxia Research Alliance (FARA) is a 501(c)(3), non-profit, tax-exempt organization formed to support the research on Friedreich's ataxia...
4 KB (287 words) - 13:19, 19 September 2023
storage protein. Reduced expression of frataxin is the cause of Friedreich's ataxia. X-ray crystallography has shown that human frataxin consists of...
22 KB (2,715 words) - 08:44, 24 February 2024
Reinforced lipids (section Friedreich's ataxia)
D2-linoleic acid ethyl ester (RT001) for Friedreich's ataxia, sponsored by Retrotope and Friedreich's Ataxia Research Alliance, was conducted to determine...
13 KB (1,307 words) - 23:59, 20 April 2024
Deulinoleate ethyl (section Friedreich's ataxia)
comparator-controlled Phase I/II clinical trial for Friedreich's ataxia, sponsored by Retrotope and Friedreich's Ataxia Research Alliance, was conducted to determine...
9 KB (802 words) - 05:31, 28 May 2024