In excitotoxicity, nerve cells suffer damage or death when the levels of otherwise necessary and safe neurotransmitters such as glutamate become pathologically...

oxidative stress and excitotoxicity—both of which are highly associated with CNS disorders. Not only can oxidative stress and excitotoxicity trigger neuron...

NMDA receptors, causing excessive influx of Ca2+ can lead to excitotoxicity. Excitotoxicity is implied to be involved in some neurodegenerative disorders...

Histamine Receptors". "Excitotoxicity and Cell Damage". 2010. M. Aarts; M. Tymianski (2003-09-15). "Novel treatment of excitotoxicity: targeted disruption...

cascade of excitotoxic cell death and further increased extracellular glutamate concentrations. Glutamate receptors' significance in excitotoxicity also links...

secondary injury. Imbalances in some neurotransmitters can lead to excitotoxicity, damage to brain cells that results from overactivation of biochemical...

cationic influx is glutamate, an excitatory neurotransmitter that triggers excitotoxicity during anoxic depolarization. A number of ionotropic receptors have...

against oxidative stress, such as that produced by glutamate-induced excitotoxicity. THC targets receptors in a manner far less selective than endocannabinoid...

LD50 is also unknown. ODAP activates AMPA receptors which can induce excitotoxicity, or overstimulation of glutamate receptors. The release of too much...

kainate receptors. In experiments, it is used to counter glutamate excitotoxicity. NBQX was found to have anticonvulsant activity in rodent seizure models...