• Thumbnail for Drosha
    Drosha is a Class 2 ribonuclease III enzyme that in humans is encoded by the DROSHA (formerly RNASEN) gene. It is the primary nuclease that executes the...
    17 KB (2,058 words) - 16:02, 21 December 2023
  • Thumbnail for Flag of Georgia (country)
    sakartvelos sakhelmts'ipo drosha), also known as the five-cross flag (Georgian: ხუთჯვრიანი დროშა, romanized: khutjvriani drosha), is one of the national...
    16 KB (1,398 words) - 02:03, 1 June 2024
  • Thumbnail for MicroRNA
    enzyme Drosha, a protein that cuts RNA, to form the Microprocessor complex. In this complex, DGCR8 orients the catalytic RNase III domain of Drosha to liberate...
    146 KB (16,588 words) - 05:54, 3 June 2024
  • Thumbnail for Microprocessor complex subunit DGCR8
    melanogaster and Caenorhabditis elegans, the protein is known as Pasha (partner of Drosha). It is a required component of the RNA interference pathway. The subunit...
    6 KB (744 words) - 12:45, 5 April 2024
  • Thumbnail for Microprocessor complex
    animal cells. The complex is minimally composed of the ribonuclease enzyme Drosha and the dimeric RNA-binding protein DGCR8 (also known as Pasha in non-human...
    18 KB (1,935 words) - 07:02, 6 May 2024
  • Thumbnail for Shiur
    the former above, baalebatim focused, is a vort, while the latter is a drosha. Especially in Chasidic settings, a less formal—often inspirational—shiur...
    13 KB (1,364 words) - 04:13, 10 January 2024
  • family, like DROSHA, play a role in processing precursor rRNAs, contributing to the assembly of functional ribosomes. DICER and DROSHA also from the...
    25 KB (2,688 words) - 21:18, 6 April 2024
  • Thumbnail for Gene expression
    stem-loop structures known as pre-miRNA in the cell nucleus by the enzymes Drosha and Pasha. After being exported, it is then processed to mature miRNAs in...
    102 KB (11,437 words) - 03:08, 13 June 2024
  • Thumbnail for Short hairpin RNA
    choice. The product mimics pri-microRNA (pri-miRNA) and is processed by Drosha. The resulting pre-shRNA is exported from the nucleus by Exportin 5. This...
    10 KB (1,259 words) - 12:22, 22 February 2024
  • Thumbnail for Mnemiopsis
    proteins Drosha and Pasha, which are critical to canonical microRNA biogenesis. It is the only animal thus far reported to be missing Drosha. MicroRNAs...
    19 KB (2,174 words) - 06:25, 4 May 2024