Drosha is a Class 2 ribonuclease III enzyme that in humans is encoded by the DROSHA (formerly RNASEN) gene. It is the primary nuclease that executes the...
17 KB (2,058 words) - 16:02, 21 December 2023
sakartvelos sakhelmts'ipo drosha), also known as the five-cross flag (Georgian: ხუთჯვრიანი დროშა, romanized: khutjvriani drosha), is one of the national...
16 KB (1,398 words) - 02:03, 1 June 2024
enzyme Drosha, a protein that cuts RNA, to form the Microprocessor complex. In this complex, DGCR8 orients the catalytic RNase III domain of Drosha to liberate...
146 KB (16,588 words) - 05:54, 3 June 2024
melanogaster and Caenorhabditis elegans, the protein is known as Pasha (partner of Drosha). It is a required component of the RNA interference pathway. The subunit...
6 KB (744 words) - 12:45, 5 April 2024
animal cells. The complex is minimally composed of the ribonuclease enzyme Drosha and the dimeric RNA-binding protein DGCR8 (also known as Pasha in non-human...
18 KB (1,935 words) - 07:02, 6 May 2024
the former above, baalebatim focused, is a vort, while the latter is a drosha. Especially in Chasidic settings, a less formal—often inspirational—shiur...
13 KB (1,364 words) - 04:13, 10 January 2024
family, like DROSHA, play a role in processing precursor rRNAs, contributing to the assembly of functional ribosomes. DICER and DROSHA also from the...
25 KB (2,688 words) - 21:18, 6 April 2024
stem-loop structures known as pre-miRNA in the cell nucleus by the enzymes Drosha and Pasha. After being exported, it is then processed to mature miRNAs in...
102 KB (11,437 words) - 03:08, 13 June 2024
choice. The product mimics pri-microRNA (pri-miRNA) and is processed by Drosha. The resulting pre-shRNA is exported from the nucleus by Exportin 5. This...
10 KB (1,259 words) - 12:22, 22 February 2024
proteins Drosha and Pasha, which are critical to canonical microRNA biogenesis. It is the only animal thus far reported to be missing Drosha. MicroRNAs...
19 KB (2,174 words) - 06:25, 4 May 2024