inhibitor 1B (p27Kip1) is an enzyme inhibitor that in humans is encoded by the CDKN1B gene. It encodes a protein which belongs to the Cip/Kip family of cyclin...
41 KB (5,152 words) - 05:27, 10 February 2024
Cyclin-dependent kinase 6 p21 / WAF1 CDKN1A Cyclin E1/Cyclin-dependent kinase 2 p27 CDKN1B Cyclin D3/Cyclin-dependent kinase 4, Cyclin E1/Cyclin-dependent kinase 2...
10 KB (1,169 words) - 22:58, 20 September 2023
binding affinity. Known CDK inhibitors are p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Drugs that inhibit Cdk2 and arrest the cell cycle, such as GW8510 and...
35 KB (4,286 words) - 18:02, 27 April 2024
a fourth form of multiple endocrine neoplasia ("MEN4"), associated with CDKN1B. The presentation is believed to overlap that of MEN1 and MEN2. The MEN1...
20 KB (2,138 words) - 04:17, 4 March 2024
trastuzumab activates is the tumor suppressor p27 (kip1), also known as CDKN1B. Trastuzumab has been shown to inhibit HER2/neu ectodomain cleavage in breast...
67 KB (5,895 words) - 12:08, 7 May 2024
P27 may refer to: CDKN1B, cyclin-dependent kinase inhibitor 1B ČZ vz. 27, a pistol IFI27, interferon alpha-inducible protein 27 Papyrus 27, a biblical...
411 bytes (88 words) - 00:10, 20 October 2022
the cell cycle and also has putative interactions with proteins CDKN1A, CDKN1B, and CDK3. Aberrant expression can lead to cancer. Gudas JM, Payton M, Thukral...
2 KB (158 words) - 22:46, 27 March 2024
and transcribe Cyclin A and Cdc 6. Cyclin-dependent kinase inhibitor 1B (CDKN1B), also known as p27, binds to and prevents the activation of CyclinE:Cdk2...
34 KB (4,581 words) - 11:50, 4 April 2024
HGNC:19287 Q5MAI5 2691 CDKL5 HGNC:11411 O76039 2692 CDKN1A HGNC:1784 P38936 2693 CDKN1B HGNC:1785 P46527 2694 CDKN1C HGNC:1786 P49918 2695 CDKN2A HGNC:1787 P42771...
277 KB (17 words) - 23:17, 27 April 2024
and prevent or reverse hearing loss. The cell cycle inhibitor p27kip1 (CDKN1B) has also been found to encourage regrowth of cochlear hair cells in mice...
30 KB (3,443 words) - 20:28, 21 May 2024