First air date
(Links to video) | Interviewee(s) | Interviewer(s) | Book | Topic of interview / Comments |
| January 2, 2010 | Gail Collins | Gwen Ifill | When Everything Changed: The Amazing Journey of American Women from 1960 to the Present | |
| January 9, 2010 | David Wessel | Alice Rivlin | In Fed We Trust: Ben Bernanke's War on the Great Panic | Ben Bernanke, Financial crisis of 2007–2008 |
| January 16, 2010 | Peniel Joseph | Kevin Merida | Dark Days, Bright Nights: From Black Power to Barack Obama | |
| January 23, 2010 | Thomas Fleming | Barbara Mitnick | The Intimate Lives of the Founding Fathers | Founding Fathers of the United States |
| January 30, 2010 | John Yoo | Victoria Toensing | Crisis and Command | |
| February 6, 2010 | Joseph Stiglitz | Lori Wallach | Freefall | Financial crisis of 2007–2008 |
| February 13, 2010 | Garry Wills | Tom Blanton | Bomb Power | |
| February 20, 2010 | Ken Gormley | Greg Craig | The Death of American Virtue: Clinton v. Starr | Impeachment of Bill Clinton |
| February 27, 2010 | George Packer | Christopher Hitchens | Facing Unpleasant Facts and All Art Is Propaganda | George Orwell |
| March 13, 2010 | Bill and Janet Cohen | John Lewis | Race & Reconciliation | |
| March 21, 2010 | Diane Ravitch | Valerie Strauss | The Death and Life of the Great American School System | |
| March 27, 2010 | Bill Bennett | Walter Isaacson | A Century Turns | |
| April 3, 2010 | Jack Matlock | Dimitri Simes | Superpower Illusions: How Myths and False Ideologies Led America Astray - and How to Return to Reality | |
| April 10, 2010 | Deborah Amos | Mohamad Bazzi | Eclipse of the Sunnis | Sunni Islam |
| April 17, 2010 | Harry Markopolos | Nicole Gelinas | No One Would Listen | Madoff investment scandal |
| April 24, 2010 | Mark Perry | Larry Johnson | Talking to Terrorists | |
| May 1, 2010 | Elaine Tyler | Christina Hoff Sommers | America and the Pill: A History of Promise, Peril, and Liberation | The birth control pill, Margaret Sanger, Katharine McCormick |
| May 8, 2010 | Piper Kerman | Ted Conover | Orange is the New Black: My Year in a Women's Prison | |
| May 15, 2010 | John Kiriakou | Frederick Hitz | The Reluctant Spy | |
| May 22, 2010 | Michael Graham | Jonathan Karl | That's No Angry Mob, That's My Mom | The Tea Party movement |
| May 29, 2010 | Sebastian Junger | Paul Rieckhoff | War | 173rd Airborne Brigade Combat Team in Afghanistan, 2007-2008 |
| May 31, 2010 | Mitt Romney | Juan Williams | No Apology: The Case for American Greatness | |
| June 5, 2010 | Stephen Prothero | Sally Quinn | God is Not One | Conceptions of God |
| June 13, 2010 | Gary Rivlin | Heather Mac Donald | Broke USA | |
| June 26, 2010 | Jere Van Dyk | George Packer | Captive: My Time As A Prisoner of the Taliban | |
| July 10, 2010 | Andrew Napolitano | Ralph Nader | Lies the Government Told You | |
| July 11, 2010 | Arthur Brooks and Strobe Talbott | The Battle: How the Fight between Free Enterprise and Big Government Will Shape America's Future (by Brooks) and Fast Forward: Ethics and Politics in the Age of Global Warming (by Talbott) | Brooks and Talbott interviewed each other about the other's book. |
| July 17, 2010 | Alan Brinkley | Sam Tanenhaus | The Publisher: Henry Luce and His American Century | Henry Luce |
| July 24, 2010 | Ayaan Hirsi Ali | Paula Dobriansky | Nomad | |
| July 31, 2010 | Carl Cannon | Paul Clement | Circle of Greed | William Lerach |
| August 7, 2010 | Richard Whittle | John Pike | The Dream Machine | V-22 Osprey |
| August 14, 2010 | Peter Beinart | Mike Allen | The Icarus Syndrome | |
| August 21, 2010 | Michael Belfiore | Joanne Carney | The Department of Mad Scientists: How DARPA Is Remaking Our World, from the Internet to Artificial Limbs | DARPA |
| August 28, 2010 | Sebastian Mallaby | Gillian Tett | More Money Than God: Hedge Funds and the Making of a New Elite | Hedge funds |
| September 4, 2010 | David Kilcullen | Lawrence Wilkerson | Counterinsurgency | Counterinsurgency |
| September 11, 2010 | Arianna Huffington | Maria Bartiromo | Third World America: How Our Politicians Are Abandoning the Middle Class and Betraying the American Dream | |
| September 18, 2010 | Gabriel Schoenfeld | Michael Mukasey | Necessary Secrets: National Security, the Media, and the Rule of Law | |
| September 27, 2010 | Louise Knight | Dan Moshenberg | Jane Addams: Spirit in Action | Jane Addams |
| October 3, 2010 | James Swanson | Edna Greene Medford | Bloody Crimes | Jefferson Davis, Funeral and burial of Abraham Lincoln |
| October 9, 2010 | Hooman Majd | Hamid Dabashi | The Ayatollah's Democracy | Politics of Iran |
| October 16, 2010 | Maria Bartiromo | Yves Smith | The Weekend That Changed Wall Street | |
| October 23, 2010 | Dinesh D'Souza | Jonathan Alter | The Roots of Obama's Rage | |
| November 1, 2010 | Scott Rasmussen and Doug Schoen | Amity Shlaes | Mad as Hell | Tea Party movement |
| November 14, 2010 | Nigel Hamilton | Richard Norton Smith | American Caesars | |
| November 20, 2010 | John Dower | Sanho Tree | Cultures of War | |
| November 21, 2010 | Ron Christie | Janet Langhart Cohen | Acting White | |
| November 28, 2010 | James Zogby | Barbara Slavin | Arab Voices: What They Are Saying to Us and Why it Matters | |
| December 11, 2010 | Noah Feldman | Dahlia Lithwick | Scorpions: The Battles and Triumphs of FDR's Great Supreme Court Justices | Felix Frankfurter, Hugo Black, Robert Jackson, William O. Douglas |
| December 12, 2010 | Jimmy Carter | Doug Brinkley | White House Diary | |
| December 18, 2010 | Hugh Shelton | William Cohen | Without Hesitation: The Odyssey of an American Warrior | |
| December 27, 2010 | Jane Smiley | Cecilia Kang | The Man Who Invented the Computer | John Vincent Atanasoff |
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