Pleiotropy (from Greek πλείων pleion, 'more', and τρόπος tropos, 'way') occurs when one gene influences two or more seemingly unrelated phenotypic traits...
40 KB (4,796 words) - 16:07, 17 May 2024
In pharmacology, pleiotropy includes all of a drug's actions other than those for which the agent was specifically developed. It may include adverse effects...
3 KB (291 words) - 16:32, 8 April 2024
The antagonistic pleiotropy hypothesis was first proposed in a 1952 paper on the evolutionary theory of ageing by Peter Medawar and developed further in...
19 KB (2,342 words) - 15:35, 12 May 2024
Evolution of ageing (section Antagonistic pleiotropy)
classical theories of evolution (mutation accumulation, antagonistic pleiotropy, and disposable soma) suggest that environmental factors, such as predation...
54 KB (6,763 words) - 11:47, 18 April 2024
pleiotropy in the interleukin-4/13 system", Cell, 132(2):259-72. Ozaki, K; Leonard, WJ (16 August 2002). "Cytokine and cytokine receptor pleiotropy and...
2 KB (216 words) - 11:13, 8 November 2022
Strawberry roan (section Health and pleiotropy)
Strawberry roan, or chestnut roan, is a horse coat color consisting of a mixture of reddish-brown and white hairs in varying proportions, stable over the...
34 KB (3,707 words) - 16:43, 1 May 2024
Domestication of vertebrates (section Pleiotropy)
putative cause for the broad changes seen in domestication syndrome is pleiotropy. Pleiotropy occurs when one gene influences two or more seemingly unrelated...
70 KB (7,806 words) - 18:18, 22 February 2024
evolution such as kin selection and inclusive fitness or antagonistic pleiotropy that favors heterozygotes producing homosexuality as a by-product. The...
135 KB (16,382 words) - 23:22, 17 June 2024
the distribution of allelic and mutational effects, and patterns of pleiotropy, dominance, and epistasis. There are several different experimental views...
13 KB (1,493 words) - 09:10, 25 May 2024
Such a genetic effect is called the antagonistic pleiotropy effect when referring to a gene (pleiotropy signifying the gene has a double function – enabling...
90 KB (10,727 words) - 08:53, 16 June 2024