Complement factor B is a protein that in humans is encoded by the CFB gene. This gene encodes complement factor B, a component of the alternative pathway...
9 KB (1,095 words) - 07:56, 3 January 2024
of complement component 3, complement factor B, and complement factor I, as well as deletion of complement factor H-related 3 and complement factor H-related...
43 KB (5,014 words) - 19:53, 25 May 2024
Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene. Complement factor I (factor I) is a protein...
18 KB (2,243 words) - 04:09, 10 March 2024
for the treatment of paroxysmal nocturnal hemoglobinuria. It is a complement factor B inhibitor that was developed by Novartis. It is taken by mouth. Iptacopan...
12 KB (739 words) - 05:08, 13 June 2024
Factor H (FH) is a member of the regulators of complement activation family and is a complement control protein. It is a large (155 kilodaltons), soluble...
29 KB (3,482 words) - 14:59, 4 June 2024
Factor D (EC 3.4.21.46, C3 proactivator convertase, properdin factor D esterase, factor D (complement), complement factor D, CFD, adipsin) is a protein...
18 KB (2,047 words) - 23:18, 16 August 2023
activation process: Complement Receptor 1 (CR1 or CD35) and DAF (decay accelerating factor also known as CD55) compete with Factor B in binding with C3b...
7 KB (865 words) - 02:42, 26 April 2024
Macular degeneration (section Risk factors)
at location 10q26 Complement Factor B/Complement Component 2 (CFB/CC2) on chromosome 6 at 6p21.3 Polymorphisms in genes for complement system proteins:...
90 KB (9,840 words) - 07:29, 23 May 2024
agent. Factor I can cleave C3b into C3c and C3d, the latter of which plays a role in enhancing B cell responses. In the alternative complement pathway...
13 KB (1,519 words) - 19:10, 19 April 2024