Pleiotropy (from Greek πλείων pleion, 'more', and τρόπος tropos, 'way') occurs when one gene influences two or more seemingly unrelated phenotypic traits...

The antagonistic pleiotropy hypothesis was first proposed in a 1952 paper on the evolutionary theory of ageing by Peter Medawar and developed further in...

In pharmacology, pleiotropy includes all of a drug's actions other than those for which the agent was specifically developed. It may include adverse effects...

classical theories of evolution (mutation accumulation, antagonistic pleiotropy, and disposable soma) suggest that environmental factors, such as predation...

pleiotropy in the interleukin-4/13 system", Cell, 132(2):259-72. Ozaki, K; Leonard, WJ (16 August 2002). "Cytokine and cytokine receptor pleiotropy and...

putative cause for the broad changes seen in domestication syndrome is pleiotropy. Pleiotropy occurs when one gene influences two or more seemingly unrelated...

evolution such as kin selection and inclusive fitness or antagonistic pleiotropy that favors heterozygotes producing homosexuality as a by-product. The...

Strawberry roan, or chestnut roan, is a horse coat color consisting of a mixture of reddish-brown and white hairs in varying proportions, stable over the...

the distribution of allelic and mutational effects, and patterns of pleiotropy, dominance, and epistasis. There are several different experimental views...

Such a genetic effect is called the antagonistic pleiotropy effect when referring to a gene (pleiotropy signifying the gene has a double function – enabling...