Pleiotropy (from Greek πλείων pleion, 'more', and τρόπος tropos, 'way') occurs when one gene influences two or more seemingly unrelated phenotypic traits...
40 KB (4,796 words) - 16:07, 17 May 2024
In pharmacology, pleiotropy includes all of a drug's actions other than those for which the agent was specifically developed. It may include adverse effects...
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The antagonistic pleiotropy hypothesis was first proposed in a 1952 paper on the evolutionary theory of ageing by Peter Medawar and developed further in...
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Evolution of ageing (section Antagonistic pleiotropy)
classical theories of evolution (mutation accumulation, antagonistic pleiotropy, and disposable soma) suggest that environmental factors, such as predation...
54 KB (6,763 words) - 11:47, 18 April 2024
evolution such as kin selection and inclusive fitness or antagonistic pleiotropy that favors heterozygotes producing homosexuality as a by-product. The...
137 KB (16,630 words) - 02:45, 9 June 2024
pleiotropy in the interleukin-4/13 system", Cell, 132(2):259-72. Ozaki, K; Leonard, WJ (16 August 2002). "Cytokine and cytokine receptor pleiotropy and...
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the distribution of allelic and mutational effects, and patterns of pleiotropy, dominance, and epistasis. There are several different experimental views...
13 KB (1,493 words) - 09:10, 25 May 2024
Strawberry roan (section Health and pleiotropy)
Strawberry roan, or chestnut roan, is a horse coat color consisting of a mixture of reddish-brown and white hairs in varying proportions, stable over the...
34 KB (3,707 words) - 16:43, 1 May 2024
Such a genetic effect is called the antagonistic pleiotropy effect when referring to a gene (pleiotropy signifying the gene has a double function – enabling...
90 KB (10,723 words) - 04:22, 3 June 2024
A very simple genotype–phenotype map that only shows additive pleiotropy effects....
2 KB (184 words) - 01:35, 27 February 2024