• Thumbnail for Sphingolipid
    Sphingolipids are a class of lipids containing a backbone of sphingoid bases, which are a set of aliphatic amino alcohols that includes sphingosine. They...
    24 KB (2,782 words) - 19:36, 29 May 2024
  • Thumbnail for Prosaposin
    cleavage products: saposins A, B, C, and D. Saposin is an acronym for Sphingolipid Activator PrO[S]teINs. Each domain of the precursor protein is approximately...
    14 KB (1,790 words) - 10:03, 27 March 2024
  • with an unsaturated hydrocarbon chain, which forms a primary part of sphingolipids, a class of cell membrane lipids that include sphingomyelin, an important...
    4 KB (219 words) - 13:26, 11 May 2024
  • Thumbnail for ORMDL1
    ORMDL sphingolipid biosynthesis regulator 1 is a protein that in humans is encoded by the ORMDL1 gene. GRCh38: Ensembl release 89: ENSG00000128699 – Ensembl...
    2 KB (209 words) - 16:05, 30 March 2024
  • Thumbnail for Ormdl sphingolipid biosynthesis regulator 3
    ORMDL sphingolipid biosynthesis regulator 3 is a protein that in humans is encoded by the ORMDL3 gene. Variants affecting the expression of this gene are...
    10 KB (1,031 words) - 23:08, 7 April 2024
  • Thumbnail for Ceramide
    bilayer. Contrary to previous assumptions that ceramides and other sphingolipids found in cell membrane were purely supporting structural elements, ceramide...
    29 KB (3,310 words) - 03:20, 2 February 2024
  • Thumbnail for Sphingosine kinase
    formation sphingosine-1-phosphate (S1P) from the precursor sphingolipid sphingosine. Sphingolipid metabolites, such as ceramide, sphingosine and sphingosine-1-phosphate...
    6 KB (627 words) - 09:37, 14 December 2023
  • Sphinganine C4-monooxygenase (EC 1.14.13.169, sphingolipid C4-hydroxylase, SUR2 (gene), SBH1 (gene), SBH2 (gene)) is an enzyme with systematic name sphinganine...
    2 KB (197 words) - 15:51, 26 August 2023
  • Delta8-fatty-acid desaturase (EC 1.14.19.4, Delta8-sphingolipid desaturase, EFD1, BoDES8, SLD, Delta8 fatty acid desaturase, Delta8-desaturase) is an enzyme...
    3 KB (275 words) - 13:46, 26 August 2023
  • Thumbnail for Lipid signaling
    sphingosine backbone. Alternatively, this sphingosine-derived lipid (sphingolipid) can be synthesized from scratch (de novo) by the enzymes serine palmitoyl...
    55 KB (5,635 words) - 16:43, 24 March 2024