(AN2) or oculorhombin, is a protein that in humans is encoded by the PAX6 gene. PAX6 is a member of the Pax gene family which is responsible for carrying...

ataxia). The AN2 region of the short arm of chromosome 11 (11p13) includes the PAX6 gene (named for its PAired boX status), whose gene product helps regulate...

factors include the genes EMX2 and PAX6. Together, both transcription factors form an opposing gradient of expression. Pax6 is highly expressed at the rostral...

the PAX6 ocular development gene and the Wilms' tumour gene (WT1). Abnormalities in WT1 may also cause genitourinary anomalies. Mutations in the PAX6 gene...

due to independent variants of Pax6 arising in both cephalopods and vertebrates. Cephalopods contain five variants of Pax6 in their genomes which independently...

Foundation for the Blind, genetic dissection of Pax6 dosage requirements in the developing eye has shown that Pax6 dosage in the lens and cornea affects the...

and usually a partial, or in the case of four family members (PAX3, PAX4, PAX6 and PAX7), a complete homeodomain to the C-terminus. An octapeptide as well...

proven, it is thought that SHH emitted from the prechordal plate suppresses Pax6, which causes the eye field to divide into two. If the SHH gene is mutated...

genetic heterogeneity characteristic of ASD. In the most recent research, the PAX6 gene has been implicated in Peters' Anomaly This congenital anomaly was first...

master control gene PAX6, a homeobox gene with known homologues in humans (aniridia), mice (small eye), and Drosophila (eyeless). The PAX6 gene locus is a...